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CD63 Polyclonal Antibody, 50ul[BT-AP01594] High Speed Micro-Centrifuges The phosphorylation of five tyrosine

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CD63 Polyclonal Antibody, 50ul[BT-AP01594] High Speed Micro-Centrifuges The phosphorylation of five tyrosineThe product of CDC42EP4 is a member of the CDC42 binding protein family. Members of this family interact with Rho family GTPases and regulate the organization of the actin cytoskeleton. This protein has been shown to bind both CDC42 and TC10 GTPases in a GTP dependent manner. When overexpressed in fibroblasts, this protein was able to induce pseudopodia formation, which suggested a role in inducing actin filament assembly and cell shape control.

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Description

The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation

Methylation of the CpG island leads to transcriptional silencing of this gene

embryo gastrulation and left-right axis determination

The encoded protein is localized to the apical membrane and is involved in apical absorption of sodium

Mutations in GATA1 have been associated with X-linked dyserythropoietic anemia and thrombocytopenia

CD63 Polyclonal Antibody, 50ul[BT-AP01594] High Speed Micro-Centrifuges The phosphorylation of five tyrosineThe product of CDC42EP4 is a member of the CDC42 binding protein family. Members of this family interact with Rho family GTPases and regulate the organization of the actin cytoskeleton. This protein has been shown to bind both CDC42 and TC10 GTPases in a GTP dependent manner. When overexpressed in fibroblasts, this protein was able to induce pseudopodia formation, which suggested a role in inducing actin filament assembly and cell shape control.

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