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In addition to several hydrophobic interactions, the polar amino acid side chains (Ser8, Ser11, Glu3, and Glu15) form hydrogen bonds with specific amino acids in the receptor

L-carnitine is the only substance that can transport long-chain fatty acids deep into the mitochondria, where they are burned

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Research has unveiled variants of the peroxisome PPARGC1B in macrophages derived from patients suffering from gouty arthritis, notably the missense single nucleotide polymorphism rs45520937