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Here are some common symptoms associated with leaky gut: Gastrointestinal symptoms: Abdominal pain (Source 5) Constipation (Source 6) Diarrhea (Source 7) Dysbiosis, an imbalance in the microbiome (Source 8) Gastroenteritis, an infection in stomach or intestines (Source 9) Hypochlorhydria, low stomach acid (Source 10) Systemic symptoms of leaky gut may include: Brain fog (Source 11) Depression (Source 12) Fatigue (Source 13) Food sensitivities (Source 14) Inflammation (Source 15) In addition to these digestive and general symptoms, leaky gut is associated with a wide range of autoimmune, metabolic and other diseases or conditions