Genz-644282 icheliolide 42(4):571-6

42(4):571-6

Molecular Weight: 578

Tebipenem is formulated as the ester tebipenem pivoxil due to the better absorption and improved bioavailability of this form

Doripenem is the most active carbapenem (MIC90

6-OAU(GTPL5846

Genz-644282 icheliolide 42(4):571-6Genz 644282, also known as SAR402674, is a non camptothecin inhibitor of topoisomerase I with potential antineoplastic activity. Topoisomerase I inhibitor Genz 644282 binds to and inhibits the enzyme topoisomerase I, which may result in the inhibition of repair of single strand DNA breaks, DNA replication, and tumor cell growth in susceptible tumor cell populations. Product information CAS Number: 529488 28 6 Molecular Weight: 407. 42 Formula: