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Trimethylamine N-oxide - CAS# 1184-78-7 0090 02 μM for Hep 3B

SKU: 93306511544

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Trimethylamine N-oxide - CAS# 1184-78-7 0090 02 μM for Hep 3BTrimethylamine N oxide, CAS No. 1184 78 7, is a gut microbe dependent metabolite of dietary choline and other trimethylamine containing nutrients. Trimethylamine N oxide induces inflammation by activating the ROS NLRP3 inflammasome. Trimethylamine N oxide also accelerates fibroblast myofibroblast differentiation and induces cardiac fibrosis by activating the TGF smad2 signaling pathway. Product information CAS Number: 1184 78 7 Molecular Weight: 75.

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Description

02 μM for Hep 3B

identified by a high-throughput

under conditions in which the only other kinase tested that is significantly inhibited is MSK1 whose activity is reduced ~5-fold

and DNA-binding

Inhibitory effect of TAS-301

Trimethylamine N-oxide - CAS# 1184-78-7 0090 02 μM for Hep 3BTrimethylamine N oxide, CAS No. 1184 78 7, is a gut microbe dependent metabolite of dietary choline and other trimethylamine containing nutrients. Trimethylamine N oxide induces inflammation by activating the ROS NLRP3 inflammasome. Trimethylamine N oxide also accelerates fibroblast myofibroblast differentiation and induces cardiac fibrosis by activating the TGF smad2 signaling pathway. Product information CAS Number: 1184 78 7 Molecular Weight: 75.

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