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A large percentage of ADPKD patients on dialysis die each year while waiting for a donated kidney. The authors wrote, Autosomal dominant polycystic kidney disease (ADPKD), caused by mutations in either PKD1 or PKD2 genes, is one of the most common human monogenetic disorders and the leading genetic cause of end-stage renal disease. The researchers explained that ADPKD has a progressive course until the kidneys are swollen with the cysts and the organ fails