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For instance, the combination study mentioned earlier used RigiScan to show men had erections above a certain rigidity threshold for a significantly longer total duration with PT-141+sildenafil than with sildenafil alone.While not used in routine practice, such objective measures can confirm the physiological effect of PT-141

Howard Fillit of the Alzheimer's Drug Discovery Foundation, which funds Alzheimer's research including the liraglutide study, said Novo's trials could shed light on the impact of GLP-1s on age-related changes to brain metabolism that occur before the formation of amyloid plaques