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When used for overweight or obesity, the drugs are typically prescribed in higher doses than when prescribed for diabetes

Hou Y, Ernst SA, Heidenreich K, and Williams JA

Mechanisms of Action and Therapeutic Rationale Physiological Basis of GLP-1 Action GLP-1, an incretin hormone, plays a crucial role in glucose metabolism and appetite regulation, influencing insulin secretion, insulin-sensitivity, and gastric emptying [15] [16]

What Fertility Specialists Actually Recommend Most reproductive endocrinologists take a more conservative approach than manufacturer guidelines: The 3-month protocol (most common recommendation): Last injection Wait 3 full months Begin actively trying to conceive The rationale for the longer timeline is multifaceted

Studies in the pig showed GLP-1 inhibited pancreatic secretion induced by hypoglycemia (central neural stimulation) but not that due to vagal nerve stimulation (126)

According to the company, all are in process and fully funded with existing corporate resources, targeting results in Q3Q4 2026