RFOX1 Polyclonal Antibody, 20ul Enzymes & Activity Assays in the presence of NADPH
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RFOX1 Polyclonal Antibody, 20ul Enzymes & Activity Assays in the presence of NADPHThe Fox 1 family of RNA binding proteins is evolutionarily conserved, and regulates tissue specific alternative splicing in metazoa. Fox 1 recognizes a (U)GCAUG stretch in regulated exons or in flanking introns. The protein binds to the C terminus of ataxin 2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin 2 is the product of the SCA2 gene which causes familial neurodegenerative diseases. Fox 1 and ataxin
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