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SBI-0206965 - Autophagy Kinase ULK1 Inhibitor. CAS# 1884220-36-3 Catalog No.:M60268-10S identified by a high-throughput screening

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SBI-0206965 - Autophagy Kinase ULK1 Inhibitor. CAS# 1884220-36-3 Catalog No.:M60268-10S identified by a high-throughput screeningSBI 0206965, CAS No. 1884220 36 3, is a potent and selective autophagy Kinase ULK1 Inhibitor. Many tumors become addicted to autophagy for survival, suggesting inhibition of autophagy as a potential broadly applicable cancer therapy. SBI 0206965 is a highly selective ULK1 kinase inhibitor in vitro and suppressed ULK1 mediated phosphorylation events in cells, regulating autophagy and cell survival. SBI 0206965 greatly synergized with mechanistic target

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Description

identified by a high-throughput screening

MK-1775 (AZD1775)

It is a natural product isolated from the corn lily (Veratrum californicum)

compound list : BAY-87-2243

It inhibits Wee1 in H3K36me3-deficient cells results in RRM2 reduction

SBI-0206965 - Autophagy Kinase ULK1 Inhibitor. CAS# 1884220-36-3 Catalog No.:M60268-10S identified by a high-throughput screeningSBI 0206965, CAS No. 1884220 36 3, is a potent and selective autophagy Kinase ULK1 Inhibitor. Many tumors become addicted to autophagy for survival, suggesting inhibition of autophagy as a potential broadly applicable cancer therapy. SBI 0206965 is a highly selective ULK1 kinase inhibitor in vitro and suppressed ULK1 mediated phosphorylation events in cells, regulating autophagy and cell survival. SBI 0206965 greatly synergized with mechanistic target

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