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Studied together, the pairing has shown meaningful improvements in HbA1c, in insulin resistance markers such as HOMA-IR, and in fat mass over roughly 52 weeks of therapy, which makes it one of the best-established and lowest-risk combinations in modern diabetes care [4]

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Signs of B12 Deficiency During GLP-1/GIP Treatment Recognising B12 deficiency can be challenging because symptoms often develop gradually and may be non-specific , particularly in patients managing diabetes or obesity who may attribute these symptoms to their underlying conditions or weight loss efforts

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pylori infections in vivo, impressively reducing drug exposure (Fig