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In addition to digestive symptoms, GLP-1s can cause dizziness, increased heart rate, headaches, and injection-site symptoms such as itchiness or redness

5.2 Acts by facilitating the synthesis of SCFAs For the gut, SCFAs have important roles in regulating intestinal microbiota balance, maintaining electrolyte balance and improving intestinal immune function

GLP-2 suppresses LPS-induced inflammation in macrophages by inhibiting ERK phosphorylation and NF-kappaB activation

Some people notice appetite changes within the first few weeks, while visible weight loss often becomes more noticeable after a few months

Once-Monthly Maridebart Cafraglutide for the Treatment of Obesity A Phase 2 Trial

Bottom line: a symptom becomes a pattern the moment it is logged next to dose day, food, and water instead of standing alone