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Why do you need B12 supplements

This is not merely additive: the MOTS-c may amplify or extend the mitochondrial biogenesis signal beyond what training alone achieves, particularly in older adults whose endogenous MOTS-c response to exercise is blunted [2]

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However, it's important to remember that no test is 100% perfect, and in rare cases, celiac disease can be present with negative antibody levels, especially if the individual is strictly adhering to a gluten-free diet