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MRX-2843 60197 a Selective TAK1 Inhibitor

SKU: 49460193153

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MRX-2843 60197 a Selective TAK1 InhibitorMRX 2843 (UNC2371) is an orally active dual inhibitor of tyrosine kinases MERTK and FLT3 with IC50 of 1. 3 nM and 0. 64 nM, respectively. Product information CAS Number: 1429882 07 4 Molecular Weight: 488. 67 Formula: C29H40N6O Synonym: UNC2371 Chemical Name: (1r,4r) 4 (2 ((2 cyclopropylethyl)amino) 5 (4 ((4 methylpiperazin 1 yl)methyl)phenyl) 7H pyrrolo[2,3 d]pyrimidin 7 yl)cyclohexanol Smiles:

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Description

a Selective TAK1 Inhibitor

PubMed PMID: 24758416

Gentile MA

Smiles: CC1=CC=CC=C1N1C(=O)C2=C(C=CC=C2C)N=C1CN1N=C(C2=C(N)N=CN=C12)C1=CC(O)=CC=C1

48(14):4535-46

MRX-2843 60197 a Selective TAK1 InhibitorMRX 2843 (UNC2371) is an orally active dual inhibitor of tyrosine kinases MERTK and FLT3 with IC50 of 1. 3 nM and 0. 64 nM, respectively. Product information CAS Number: 1429882 07 4 Molecular Weight: 488. 67 Formula: C29H40N6O Synonym: UNC2371 Chemical Name: (1r,4r) 4 (2 ((2 cyclopropylethyl)amino) 5 (4 ((4 methylpiperazin 1 yl)methyl)phenyl) 7H pyrrolo[2,3 d]pyrimidin 7 yl)cyclohexanol Smiles:

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