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8, 9, 10 This has been linked to chronic low-level inflammation induced by pro-inflammatory cytokines released by the tumor and tumor-associated macrophages (see review on cachexia in the same issue of this topical issue)

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14 The number of fibroblasts measured by HSP47 expression were highest in exendin-4 treated mice as was the number of differentiated myofibroblasts which were characterized by the presence of Acta2+ cells by immunohistochemical analysis

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