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PROTAC Bcl2 degrader-1 agonist PubMed PMID: 23030482

PROTAC Bcl2 degrader-1 agonist PubMed PMID: 23030482

Name: PROTAC Bcl2 degrader-1 agonist PubMed PMID: 23030482
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SKU: 4334332034
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PROTAC Bcl2 degrader-1 agonist PubMed PMID: 23030482PROTAC Bcl2 degrader 1 (Compound C5) is a PROTAC, which potently and selectively induces the degradation of Bcl 2 (IC50, 4. 94 M; DC50, 3. 0 M) and Mcl 1 (IC50, 11. 81 M) by introducing the E3 ligase cereblon (CRBN) binding ligand pomalidomide to Mcl 1 Bcl 2 dual inhibitor Nap 1. Product information CAS Number: 2378801 85 3 Molecular Weight: 941. 84 Formula: C45H45BrN6O10S Chemical Name: N' (2 {8 [(4 bromophenyl)sulfanyl] 2, 4 dioxo 3 azatricyclo[7.

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Description

PubMed PMID: 23030482

which is a metabolite of Ivabradine

Vesnarinone

N'-(methylenebis(4

InChi: InChI=1S/C18H11BrN2O2/c19-12-6-7-17(22)14(8-12)16-9-13(11-4-2-1-3-5-11)15(10-20)18(23)21-16/h1-9

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