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Synthesis and Characterization of Diketopiperazine Derived From AX Sodium AX (19 mg, 0.05 mmol) and DTT (15 mg, 0.1 mmol) were dissolved in 1.5 ml of degassed H 2 O under N 2 atmosphere and stirred overnight at room temperature

Studies have confirmed that NJ directly binds to the His745 and Phe903 sites of CSE1L, blocking the nuclear translocation process of the transcription factor SP1 mediated by them (Figure 7)

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