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Full therapeutic effects typically require reaching higher maintenance doses (5 mg to 15 mg weekly) after 8 to 12 weeks of dose escalation

It has gained attention and FDA approval for its effectiveness in promoting weight loss (marketed as Wegovy for weight management)

Food and Drug Administration (FDA) conducted an internal review on the safety of GLP-1s that analyzed clinical reports of suicidal thoughts associated with using those medications

Immunofluorescence staining revealed that the BM microvasculature was significantly altered and disrupted, including sinusoidal breakdown and vessel dilation (Fig

4 Conclusion and perspectives Although human kidney diseases arise from complicated pathological mechanisms and different etiologies, mitochondrial dysfunction is no doubt plays an important role in the pathogenesis