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Purvalanol A - CAS# 212844-53-6 60256 2-hydroxyglutarate (2HG)

Purvalanol A - CAS# 212844-53-6 60256 2-hydroxyglutarate (2HG)

Name: Purvalanol A - CAS# 212844-53-6 60256 2-hydroxyglutarate (2HG)
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SKU: 3471610302
Price: 20.00 USD
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SKU: 3471610302

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Purvalanol A - CAS# 212844-53-6 60256 2-hydroxyglutarate (2HG)Purvalanol A, CAS No. 212844 53 6, is a potent CDK inhibitor, which effectively suppresses Src mediated transformation by inhibiting both CDKs and c Src. indicating that the activation of CDKs contributes to the c Src transformation. Purvalanol A suppressed the c Src activity as effectively as the Src selective inhibitor PP2, and that it reverted the transformed morphology to a nearly normal shape with less cytotoxicity than PP2. Purvalanol A induced

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Description

2-hydroxyglutarate (2HG)

6-dichlorobenzamide

LOK and human HER2 with IC50 of 4

and the concentration that inhibits adhesion molecule expression

ML-329 showed specific activity against the MITF-dependent cells

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