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For patients experiencing intolerable constipation with tirzepatide, discussing alternative GLP-1 receptor agonists with their healthcare provider may be reasonable, though similar side effects may occur given the shared mechanism of action

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To address these questions, in this study we have examined the occurrence of the GLP-1R in PSCs in normal pancreas, in AP/CP models, as well as the ability of the GLP-1R agonist, liraglutide, to alter function of PSCs and effect PSCs behavior

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This was a randomized, double-blinded, placebo controlled crossover study involving 49 volunteers who consumed beer to obtain a breath alcohol content (BrAC) of 0.1 g/210L

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