AKT-IN-VIII - CAS# 612847-09-3 60211 Formula: C20H20N4O3

Formula: C20H20N4O3

24(11):1392-401

IRE-3 inhibits the XBP1 mRNA splicing through binding to the IRE1α ATP-binding site

IC50 Value: 10±0

a novel and simple chemically defined xeno-free culture system was developed that allows for long-term expansion of human pluripotent stem cells without FGF or TGF-beta pathway activation

AKT-IN-VIII - CAS# 612847-09-3 60211 Formula: C20H20N4O3AKT IN VIII, CAS No. 612847 09 3, also known as AKTi 1 2, is a potent, selective and ell permeable, allosteric inhibitor of Akt 1 and 2, which efficiently inhibits CaMKI activity and aryl hydrocarbon receptor pathway. AKT IN VIII suppresses hyperthermia induced Ndrg2 phosphorylation in gastric cancer cells. AKT IN VIII displays good selectivity against a panel of 70 other kinases with micromolar inhibition against some kinases, for example, calcium