Epalrestat - CAS# 82159-09-9 752 Smiles: COC1=CC2CC[C@H]3[C@@H]4CC[C@H](NCCCCCCN5C(=O)C=CC5=O)[C@@]4(C)CC[C@@H]3C=2C=C1

Smiles: COC1=CC2CC[C@H]3[C@@H]4CC[C@H](NCCCCCCN5C(=O)C=CC5=O)[C@@]4(C)CC[C@@H]3C=2C=C1

SB203580 at higher concentrations activates the ERK pathway

As a prodrug

InChi: InChI=1S/C17H13N3O7/c1-2-26-17(23)10-3-5-11(6-4-10)19-16(22)13(15(21)18-19)9-12-7-8-14(27-12)20(24)25/h3-9H

Smiles: O[C@@H]1CC2=C(C=C(O)C=C2O)O[C@@H]1C1=CC(O)=C(O)C(O)=C1

Epalrestat - CAS# 82159-09-9 752 Smiles: COC1=CC2CC[C@H]3[C@@H]4CC[C@H](NCCCCCCN5C(=O)C=CC5=O)[C@@]4(C)CC[C@@H]3C=2C=C1Epalrestat is an aldose reductase inhibitor that is currently available for the treatment of diabetic neuropathy. In vivo, Epalrestat treatment significantly ameliorated the bleomycin mediated histological fibrosis alterations and blocked collagen deposition concomitantly with reversing bleomycin induced expression up regulation of TGF 1, AR, SMA and collagen I (both mRNA and protein). Product information CAS Number: 82159 09 9 Molecular Weight: 319.