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NPS-2143 ycin aminonucleoside Smiles: CC1C=C(C=C(C)C=1CC1=CC=C(O)C(=C1)C(C)C)OCP(O)(O)=O

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NPS-2143 ycin aminonucleoside Smiles: CC1C=C(C=C(C)C=1CC1=CC=C(O)C(=C1)C(C)C)OCP(O)(O)=ONPS 2143 (SB 262470A), an orally active calcilytic agent, is a selective and potent calcium ion sensing receptor (CaSR) antagonist. NPS 2143 (SB 262470A) blocks increases in cytoplasmic Ca2+ concentrations (IC50=43 nM) elicited by activating the Ca2+ receptor in HEK 293 cells expressing the human Ca2+ receptor. Product information CAS Number: 284035 33 2 Molecular Weight: 408. 92 Formula: C24H25ClN2O2 Synonym: SB 262470A Related CAS Number: 324523 20

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Description

Smiles: CC1C=C(C=C(C)C=1CC1=CC=C(O)C(=C1)C(C)C)OCP(O)(O)=O

GSK 2983559

indicating reduced mitochondrial function in this nGD cell model

the regulatory CK2β subunit

4-benzodioxin-6-yl)-2

NPS-2143 ycin aminonucleoside Smiles: CC1C=C(C=C(C)C=1CC1=CC=C(O)C(=C1)C(C)C)OCP(O)(O)=ONPS 2143 (SB 262470A), an orally active calcilytic agent, is a selective and potent calcium ion sensing receptor (CaSR) antagonist. NPS 2143 (SB 262470A) blocks increases in cytoplasmic Ca2+ concentrations (IC50=43 nM) elicited by activating the Ca2+ receptor in HEK 293 cells expressing the human Ca2+ receptor. Product information CAS Number: 284035 33 2 Molecular Weight: 408. 92 Formula: C24H25ClN2O2 Synonym: SB 262470A Related CAS Number: 324523 20

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