Rat Bone Morphogenetic Protein 2, BMP-2 ELISA Kit , 96T Cellular Cultivation & Health Management where an activated MAPK kinase

where an activated MAPK kinase kinase (MAP3K) phosphorylates and activates a specific MAPK kinase (MAP2K)

Maintains myogenic progenitors pool by suppressing differentiation through down-regulation of MYOD1 and is required for satellite cell homing and PAX7 expression (PubMed: 22940113)

May enhance HIF1A function by sequestering HIF1AN away from HIF1A

|PTM:Ubiquitin-mediated proteolysis by SMAD-specific E3 ubiquitin ligase SMURF1

It was suggested that kanadaptin is an adaptor protein or chaperone involved in targeting kAE1 to the plasma membrane

Rat Bone Morphogenetic Protein 2, BMP-2 ELISA Kit , 96T Cellular Cultivation & Health Management where an activated MAPK kinaseInduces cartilage and bone formation. Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3 EIF2A ATF4 pathway. BMP2 activation of EIF2AK3 stimulates phosphorylation of EIF2A which leads to increased expression of ATF4 which plays a central role in osteoblast differentiation. In addition stimulates TMEM119, which upregulates the expression of ATF4.