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Rucaparib phosphate - CAS# 459868-92-9 dophyllotoxin CAS Number: 1421227-52-2

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Rucaparib phosphate - CAS# 459868-92-9 dophyllotoxin CAS Number: 1421227-52-2Rucaparib is a tricyclic indole poly(ADP Ribose) polymerase (PARP1) inhibitor with potential chemosensitizing, radiosensitizing, and antineoplastic activities. Rucaparib selectively binds to PARP1 and inhibits PARP1 mediated DNA repair, thereby enhancing the accumulation of DNA strand breaks and promoting genomic instability and apoptosis. Product information CAS Number: 459868 92 9 Molecular Weight: 421. 36 Formula: C19H21FN3O5P Synonym: AG014699

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Description

CAS Number: 1421227-52-2

Smiles: CN(OC)C(=O)N1N=C(S[C@]1(CCCN)C1C=CC=CC=1)C1=CC(F)=CC=C1F

is an BACE inhibitor used for the treatment of Alzheimer's Disease

Smiles: CN1C=NC=C1[C@](O)(COC1=CC=C(C=C1C1C=CC(=CC=1)OC(F)(F)F)C#N)C1C=CC(=CC=1)C#N

ACBI1 can induce anti-proliferative effects and apoptosis

Rucaparib phosphate - CAS# 459868-92-9 dophyllotoxin CAS Number: 1421227-52-2Rucaparib is a tricyclic indole poly(ADP Ribose) polymerase (PARP1) inhibitor with potential chemosensitizing, radiosensitizing, and antineoplastic activities. Rucaparib selectively binds to PARP1 and inhibits PARP1 mediated DNA repair, thereby enhancing the accumulation of DNA strand breaks and promoting genomic instability and apoptosis. Product information CAS Number: 459868 92 9 Molecular Weight: 421. 36 Formula: C19H21FN3O5P Synonym: AG014699

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