TTR mouse Monoclonal Antibody(3G7), 50ul In vitro Assessment GIT proteins regulate cytoskeletal dynamics

GIT proteins regulate cytoskeletal dynamics and participate in receptor internalization and membrane trafficking

Members of this family contain pleckstrin-homology domains

Multiple pseudogenes of this gene are located on chromosome 1

Unlike the other two isoforms

This gene is found in a cluster with other desmocollin family members on chromosome 18

TTR mouse Monoclonal Antibody(3G7), 50ul In vitro Assessment GIT proteins regulate cytoskeletal dynamicsThis gene encodes transthyretin, one of the three prealbumins including alpha 1 antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported most mutations are related to amyloid