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doi: 10.1016/j.jmgm.2008.11.005

For collagen, absorption is less dependent on an empty stomach, but it is highly dependent on co-factors

Ailments like anemia and undergone gastrointestinal surgery patients also will not have absorption ability

Obesity and cancer overview

Around the same time perimenopause typically begins, collagen production and natural antioxidant defenses also decline, so experts recommend starting glutathione in your 30s (the earlier, the better)