DNA pol lambda Polyclonal Antibody, 20ul Enzyme Activity Assays AKR1C3 shares high sequence identity

AKR1C3 shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14

These tips come with a filter for precise and contamination-free transfers

The A-I and A-IV genes are transcribed from the same strand

Transgenic studies of the mouse counterpart suggested that this gene functions as an essential initiator of apoptosis in thymocyte-negative selection

Mutations in this gene are associated with the autosomal recessive disorders cystic fibrosis and congenital bilateral aplasia of the vas deferens

DNA pol lambda Polyclonal Antibody, 20ul Enzyme Activity Assays AKR1C3 shares high sequence identityPOLL encodes a DNA polymerase. DNA polymerases catalyze DNA template directed extension of the 3' end of a DNA strand. This particular polymerase, which is a member of the X family of DNA polymerases, likely plays a role in non homologous end joining and other DNA repair processes. Alternatively spliced transcript variants have been described.