Human Toll-like Receptor 1, TLR1 ELISA Kit , 96T Tubes Specifically binds to an IL-1

Specifically binds to an IL-1 response element in the IL-6 gene

The presence of a putative bipartite nuclear localization signal suggests that VCX/Y members are nuclear proteins

Likely to power actin-based membrane trafficking in many physiologically crucial tissues

GO annotations related to this gene include G-protein coupled receptor activity and opioid receptor activity

It is proposed that this gene plays a role in mitochondrial protein metabolism and could be involved in mitochondrial pathologies

Human Toll-like Receptor 1, TLR1 ELISA Kit , 96T Tubes Specifically binds to an IL-1Participates in the innate immune response to microbial agents. Specifically recognizes diacylated and triacylated lipopeptides. Cooperates with TLR2 to mediate the innate immune response to bacterial lipoproteins or lipopeptides (PubMed: 21078852). Forms the activation cluster TLR2: TLR1: CD14 in response to triacylated lipopeptides, this cluster triggers signaling from the cell surface and subsequently is targeted to the Golgi in a lipid raft