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SP-100 Polyclonal Antibody, 100ul Plasmid Preparation DM plays a central role

SKU: 98400855392

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SP-100 Polyclonal Antibody, 100ul Plasmid Preparation DM plays a central roleSP100 (SP100 nuclear antigen) encodes a subnuclear organelle and major component of the PML (promyelocytic leukemia) SP100 nuclear bodies. PML and SP100 are covalently modified by the SUMO 1 modifier, which is considered crucial to nuclear body interactions. The encoded protein binds heterochromatin proteins and is thought to play a role in tumorigenesis, immunity, and gene regulation. Alternatively spliced variants have been identified for SP100; one

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Description

DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP (class II-associated invariant chain peptide) molecule from the peptide binding site

This gene encodes a member of the protein arginine N-methyltransferase (PRMT) family

This protein may play a role in cardiovascular development

NFE4 is located in an intron of the FBXL13 gene on the opposite strand

TAF6L encodes a protein that is a component of the PCAF histone acetylase complex and structurally similar to one of the histone-like TAFs

SP-100 Polyclonal Antibody, 100ul Plasmid Preparation DM plays a central roleSP100 (SP100 nuclear antigen) encodes a subnuclear organelle and major component of the PML (promyelocytic leukemia) SP100 nuclear bodies. PML and SP100 are covalently modified by the SUMO 1 modifier, which is considered crucial to nuclear body interactions. The encoded protein binds heterochromatin proteins and is thought to play a role in tumorigenesis, immunity, and gene regulation. Alternatively spliced variants have been identified for SP100; one

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