PNMT Rabbit Polyclonal Antibody, 20ul Site-directed Mutagenesis MAPKKK5 contains 1|374 amino acids

MAPKKK5 contains 1|374 amino acids with all 11 kinase subdomains

An important paralog of this gene is G3BP1

This kinase undergoes autophosphorylation

MIA) is a Src homology 3 (SH3)-like domain containing protein that is secreted from chondrocytes and malignant melanoma cells

Mutations in this gene are associated with complement component-6 deficiency

PNMT Rabbit Polyclonal Antibody, 20ul Site-directed Mutagenesis MAPKKK5 contains 1|374 amino acidsThe product of this gene catalyzes the last step of the catecholamine biosynthesis pathway which methylates norepinephrine to form epinephrine (adrenaline). The enzyme also has beta carboline 2N methyltransferase activity. This gene is thought to play a key step in regulating epinephrine production. Alternatively spliced transcript variants have been found for this gene.