CD274 Polyclonal Antibody, 100ul Peripheral Blood Separation Tube Several alternatively spliced transcript variants

Several alternatively spliced transcript variants have been found

frequently in association with type I collagen

Knockout studies in mice suggest that this kinase is important for lipopolysaccharide (LPS)-mediated signaling in activated macrophages and may also play a role in controlling anxiety-like behavior

a cell division cycle control protein of Sacchromyces cerevisiae

Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma

CD274 Polyclonal Antibody, 100ul Peripheral Blood Separation Tube Several alternatively spliced transcript variantsThis gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobulin V like and C like domains. Interaction of this ligand with its receptor inhibits T cell activation and cytokine production. During infection or inflammation of normal tissue, this interaction is