TPC Rabbit Polyclonal Antibody, 100ul Enzymes Runt-related transcription factor 2 is

Runt-related transcription factor 2 is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression

It encodes a calcium-dependen NADPH oxidase that generates superoxide

unlike closely related proteins

and breast cancer

It has also been shown to ubiquitinate phosphorylated NFKBIA (nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor| alpha)| targeting it for degradation and thus activating nuclear factor kappa-B

TPC Rabbit Polyclonal Antibody, 100ul Enzymes Runt-related transcription factor 2 is