PCD17 Rabbit Polyclonal Antibody, 20ul Transporters LDL receptors are transmembrane cell

LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands

The gene product interacts with certain inflammatory response factors| and polymorphisms of this gene may be involved in the pathogenesis of Alzheimer's disease

SUBCELLULAR LOCATION: Cell membrane

Also| it is thought that the presenilins are involved in the cleavage of the Notch receptor such that| they either directly regulate gamma-secretase activity| or themselves act are protease enzymes

Defects in this gene cause aortic aneurysm familial thoracic type 6

PCD17 Rabbit Polyclonal Antibody, 20ul Transporters LDL receptors are transmembrane cellThis gene belongs to the protocadherin gene family a subfamily of the cadherin superfamily. The encoded protein contains six extracellular cadherin domains a transmembrane domain and a cytoplasmic tail differing from those of the classical cadherins. The encoded protein may play a role in the establishment and function of specific cell cell connections in the brain.