Mob1A Polyclonal Antibody, 100ul[BT-AP11421] Gel & Buffers Polymorphisms in this gene may

Polymorphisms in this gene may be associated with a susceptibility for schizophrenia

is a 450 amino acid multi-pass membrane protein expressed in inner-ear tissue

The 9-1-1 complex stimulates DNA polymerase beta (POLB) activity by increasing its affinity for the 3'-OH end of the primer-template and stabilizes POLB to those sites where LP-BER proceeds

Has PARP activity and can modify TERF1

It plays a negative regulatory role in the Ras-Raf1-MAPK pathway| and knockout mice have been shown to develop spontaneous tumors| suggesting a role as a tumor suppressor gene

Mob1A Polyclonal Antibody, 100ul[BT-AP11421] Gel & Buffers Polymorphisms in this gene mayThe protein encoded by this gene is similar to the yeast Mob1 protein. Yeast Mob1 binds Mps1p, a protein kinase essential for spindle pole body duplication and mitotic checkpoint regulation. Three transcript variants encoding different isoforms have been found for this gene.