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This is where the difficulty arises

GLP-1RAs suppress NLRP3 inflammasome activation via attenuating the expression of NLRP3, apoptotic speck containing protein (ASC), and cleaves caspase 1 (p10) [111]

But having a backup plan and documenting all communications is wise

When to seek medical attention Most constipation during GLP-1 therapy resolves with dietary adjustments and lifestyle modifications

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