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AChR Alpha5 Polyclonal Antibody, 50ul Plasmid Preparation Contains 1 CBL N-terminal domain

SKU: 87743851209

4.4
USD142.00 USD179.00

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AChR Alpha5 Polyclonal Antibody, 50ul Plasmid Preparation Contains 1 CBL N-terminal domainCholinergic receptor nicotinic alpha 5 subunit encoded by CHRNA5 is a nicotinic acetylcholine receptor subunit and a member of a superfamily of ligand gated ion channels that mediate fast signal transmission at synapses. These receptors are thought to be heteropentamers composed of separate but similar subunits. Defects in this gene have been linked to susceptibility to lung cancer type 2 (LNCR2).

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Description

Contains 1 CBL N-terminal domain

including the short alpha region

which is found in proteins involved in RAB GTPase signaling and vesicle trafficking

Specifically interacts with the ligand binding domain of the thyroid hormone receptor (in a thyroid hormone T3-independent manner) and with retinoid X receptor (RXR)

Some granins have been shown to function as helper proteins in sorting and proteolytic processing of prohormones

AChR Alpha5 Polyclonal Antibody, 50ul Plasmid Preparation Contains 1 CBL N-terminal domainCholinergic receptor nicotinic alpha 5 subunit encoded by CHRNA5 is a nicotinic acetylcholine receptor subunit and a member of a superfamily of ligand gated ion channels that mediate fast signal transmission at synapses. These receptors are thought to be heteropentamers composed of separate but similar subunits. Defects in this gene have been linked to susceptibility to lung cancer type 2 (LNCR2).

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