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STAG3 Polyclonal Antibody, 50ul Organelle Studies Proteolipid protein family members are

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STAG3 Polyclonal Antibody, 50ul Organelle Studies Proteolipid protein family members areThe stromal antigen 3 encoded by STAG3 is expressed in the nucleus and is a subunit of the cohesin complex which regulates the cohesion of sister chromatids during cell division. A mutation in this gene is associated with premature ovarian failure. Alternate splicing results in multiple transcript variants encoding distinct isoforms. This gene has multiple pseudogenes.

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Description

Proteolipid protein family members are expressed in most brain regions and are thought to be involved in cellular housekeeping functions such as membrane trafficking and cell-to-cell communication

flanked by N- and C-terminal globular domains

is an integral component of the E3 ubiquitin ligase complex designated SCF

function:Specifically phosphorylates 'Tyr-504' on LCK

Increased expression of this gene is associated with some cases of leukemia

STAG3 Polyclonal Antibody, 50ul Organelle Studies Proteolipid protein family members areThe stromal antigen 3 encoded by STAG3 is expressed in the nucleus and is a subunit of the cohesin complex which regulates the cohesion of sister chromatids during cell division. A mutation in this gene is associated with premature ovarian failure. Alternate splicing results in multiple transcript variants encoding distinct isoforms. This gene has multiple pseudogenes.

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