SIRT2 Polyclonal Antibody, 20ul Enzyme Activity Assays The extracellular region possesses a

The extracellular region possesses a lengthy Pro‑rich region (aa 55‑200)

This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb)

Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers

This protease cleaves type II collagen more efficiently than types I and III

where it constitutes the regulatory subunit

SIRT2 Polyclonal Antibody, 20ul Enzyme Activity Assays The extracellular region possesses aSIRT2 encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular