PI 3-kinase p85 Alpha Polyclonal Antibody, 100ul[BT-AP07143] Molecular Sciences Mutations in this gene cause

Mutations in this gene cause Steel syndrome

and acts as a decoy receptor that inhibits the activity of its ligands

It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs)

Alternatively spliced transcript variants encoding distinct protein isoforms have been found for this gene

5-bisphosphate to 1D-myo-inositol 1

PI 3-kinase p85 Alpha Polyclonal Antibody, 100ul[BT-AP07143] Molecular Sciences Mutations in this gene causePhosphatidylinositol 3 kinase phosphorylates the inositol ring of phosphatidylinositol at the 3 prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. PIK3R1 encodes the 85 kD regulatory subunit. Phosphatidylinositol 3 kinase plays an important role in the metabolic actions of insulin, and a mutation in PIK3R1 has been associated with insulin resistance. Alternative splicing of PIK3R1