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JMY Polyclonal Antibody, 100ul Metabolic enzymes The protein is thought to

SKU: 75479255907

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JMY Polyclonal Antibody, 100ul Metabolic enzymes The protein is thought toJMY is a Protein Coding gene. Junction mediating and regulatory protein acts both as a nuclear p53 TP53 cofactor and a cytoplasmic regulator of actin dynamics depending on conditions. In nucleus, acts as a cofactor that increases p53 TP53 response via its interaction with p300 EP300. Increases p53 TP53 dependent transcription and apoptosis, suggesting an important role in p53 TP53 stress response such as DNA damage. In cytoplasm, acts as a nucleation

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Description

The protein is thought to be involved in lymphangiogenesis and maintenance of the lymphatic endothelium

Cleavage occurs at the

GTPase-activating proteins (GAPs) accelerate the intrinsic rate of GTP hydrolysis of Ras-related proteins

There is a DQHA(X)2E(X)4E motif found at the C-terminus of the protein encoded by PMS2 that forms part of the active site of the nuclease

Hirschsprung disease

JMY Polyclonal Antibody, 100ul Metabolic enzymes The protein is thought toJMY is a Protein Coding gene. Junction mediating and regulatory protein acts both as a nuclear p53 TP53 cofactor and a cytoplasmic regulator of actin dynamics depending on conditions. In nucleus, acts as a cofactor that increases p53 TP53 response via its interaction with p300 EP300. Increases p53 TP53 dependent transcription and apoptosis, suggesting an important role in p53 TP53 stress response such as DNA damage. In cytoplasm, acts as a nucleation

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