TPC1 Rabbit Polyclonal Antibody, 100ul Deep Well Plates Gene Ontology (GO) annotations related

Gene Ontology (GO) annotations related to this gene include acetylglucosaminyltransferase activity

The protein contains a C2C2-type zinc finger-like motif

The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts

Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2

Read-through transcription also exists between this gene and the downstream EGFL8 (EGF-like-domain| multiple 8) gene

TPC1 Rabbit Polyclonal Antibody, 100ul Deep Well Plates Gene Ontology (GO) annotations relatedVoltage gated Ca(2+) and Na+ channels have 4 homologous domains each containing 6 transmembrane segments S1 to S6. TPCN1 is similar to these channels but it has only 2 domains containing S1 to S6 (Ishibashi et al. 2000