Desmin Monoclonal Antibody(1B12), 50ul Antibodies Belongs to the FAM22 family

Belongs to the FAM22 family

The protein encoded by this gene has similarity to a mouse protein which suggests a role in the insertion of secretory and membrane polypeptides into the endoplasmic reticulum

PTM:Phosphorylated on Ser-13 in mitosis

resulting in the conversion of lysine to alpha-aminoadipic semialdehyde

This protease cleaves complement components C2 and C4 in order to generate C3 convertase in the lectin pathway of the complement system

Desmin Monoclonal Antibody(1B12), 50ul Antibodies Belongs to the FAM22 familyThis gene encodes a muscle specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.