EDC4 Polyclonal Antibody, 50ul Aspirating Pipets Internalization and recycling of integrin

Internalization and recycling of integrin receptors is important in cell adhesion and migration modulation

This protein is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL)

A mutation in this gene has been associated with bilateral nasolacrimal duct obstruction (LCDD)

This gene encodes a member of the acyl-CoA thioesterase family which catalyse the conversion of activated fatty acids to the corresponding non-esterified fatty acid and coenzyme A

Polymorphisms in this gene are associated with susceptibility to gastric cancers

EDC4 Polyclonal Antibody, 50ul Aspirating Pipets Internalization and recycling of integrinIn the process of mRNA degradation, seems to play a role in mRNA decapping. Component of a complex containing DCP2 and DCP1A which functions in decapping of ARE containing mRNAs. Promotes complex formation between DCP1A and DCP2. Enhances the Catalytic activity of DCP2 (in vitro).,PTM: Phosphorylated upon DNA damage, probably by ATM or ATR.,Belongs to the WD repeat EDC4 family.,Contains 4 WD repeats.,subunit: Part of a decapping complex consisting of