TIRAP(Phospho Tyr86) Polyclonal Antibody, 100ul Cell Culture Dishes Amplification and/or overexpression of this

Amplification and/or overexpression of this gene has been reported in numerous cancers

or changes in metabolism

The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop

Mutations in ITPR1 cause spinocerebellar ataxia type 15

ALDH3B1 encodes a member of the aldehyde dehydrogenase protein family

TIRAP(Phospho Tyr86) Polyclonal Antibody, 100ul Cell Culture Dishes Amplification and/or overexpression of thisThe innate immune system recognizes microbial pathogens through Toll like receptors (TLRs), which identify pathogen associated molecular patterns. Different TLRs recognize different pathogen associated molecular patterns and all TLRs have a Toll interleukin 1 receptor (TIR) domain, which is responsible for signal transduction. The protein encoded by this gene is a TIR adaptor protein involved in the TLR4 signaling pathway of the immune system. It