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KIRR1 Polyclonal Antibody, 50ul In vitro Assessment Other polypeptides of subunit VIIa

SKU: 6799320108

4.1
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KIRR1 Polyclonal Antibody, 50ul In vitro Assessment Other polypeptides of subunit VIIaNEPH1 is a member of the nephrin like protein family, which includes NEPH2 (MIM 607761) and NEPH3 (MIM 607762). The cytoplasmic domains of these proteins interact with the C terminus of podocin (NPHS2; MIM 604766), and the genes are expressed in kidney podocytes, cells involved in ensuring size and charge selective ultrafiltration (Sellin et al., 2003

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Description

Other polypeptides of subunit VIIa are present in both muscle and nonmuscle tissues| and are encoded by different genes

suggesting that

NPHS1 encodes a member of the immunoglobulin family of cell adhesion molecules that functions in the glomerular filtration barrier in the kidney

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis

Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia

KIRR1 Polyclonal Antibody, 50ul In vitro Assessment Other polypeptides of subunit VIIaNEPH1 is a member of the nephrin like protein family, which includes NEPH2 (MIM 607761) and NEPH3 (MIM 607762). The cytoplasmic domains of these proteins interact with the C terminus of podocin (NPHS2; MIM 604766), and the genes are expressed in kidney podocytes, cells involved in ensuring size and charge selective ultrafiltration (Sellin et al., 2003

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