APBA1 Polyclonal Antibody, 100ul Immunoassays Two alternatively spliced transcript variants

Two alternatively spliced transcript variants have been described for this gene

and is upregulated by nerve growth factor

Upon degradation of the inhibitor

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Mutations in this gene have been found to cause fish-eye disease as well as LCAT deficiency

APBA1 Polyclonal Antibody, 100ul Immunoassays Two alternatively spliced transcript variantsThe protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a