KMT1B Polyclonal Antibody, 20ul Cellular Function Assays Orthologs of HIRA in yeast

Orthologs of HIRA in yeast

Can also function as a repressor by recruiting histone deacetylase 3/HDAC3 to the promoter region of JUN

Two alternatively spliced transcript variants encoding the same protein have been reported

Mutations in this gene are associated with several congenital defects

GRB10 encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors

KMT1B Polyclonal Antibody, 20ul Cellular Function Assays Orthologs of HIRA in yeastHistone lysine N methyltransferase SUV39H2 is a Histone methyltransferase that specifically trimethylates Lys 9 of histone H3 using monomethylated H3 Lys 9 as substrate. H3 Lys 9 trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 (CBX1, CBX3 and or CBX5) proteins to methylated histones. Mainly functions in heterochromatin regions, thereby playing a central role in the establishment of constitutive