ST1B1 Rabbit Polyclonal Antibody, 20ul Vacuum Filter CYP8B1 encodes a member of

CYP8B1 encodes a member of the cytochrome P450 superfamily of enzymes

The encoded protein binds numerous other proteins including group I metabotropic glutamate receptors| inositol 1|4|5-trisphosphate receptors and amyloid precursor proteins and has been implicated in diverse biological functions such as neuronal signaling| T-cell activation and trafficking of amyloid beta peptides

The encoded protein may be a marker for chromosome aneuploidy as well as an autoantigen in Sjogren's syndrome

Pseudogenes corresponding to MRPS17 are found on chromosomes 1p

Gene Ontology (GO) annotations related to this gene include poly(A) RNA binding

ST1B1 Rabbit Polyclonal Antibody, 20ul Vacuum Filter CYP8B1 encodes a member ofSulfotransferase enzymes catalyze the sulfate conjugation of many hormones neurotransmitters drugs and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. However the total genomic length of this gene is greater than that of other SULT1 genes.