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PARP-1 (Acetyl-K521) Polyclonal Antibody, 20ul Recombinant Ab Production and may play a role

SKU: 6202909646

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PLN111.00 PLN150.00

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PARP-1 (Acetyl-K521) Polyclonal Antibody, 20ul Recombinant Ab Production and may play a roleThis gene encodes a chromatin associated enzyme, poly(ADP ribosyl)transferase, which modifies various nuclear proteins by poly(ADP ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be

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Description

and may play a role in regulating the actin cytoskeleton

frequently in association with type I collagen

Also acts as a positive regulator of the Wnt signaling pathway

Mutations in this gene are associated with Mitchell-Riley syndrome| which is characterized by neonatal diabetes with pancreatic hypoplasia| duodenal and jejunal atresia| and gall bladder agenesis

a subset of spliceosomal snRNAs are exported from the nucleus after transcription

PARP-1 (Acetyl-K521) Polyclonal Antibody, 20ul Recombinant Ab Production and may play a roleThis gene encodes a chromatin associated enzyme, poly(ADP ribosyl)transferase, which modifies various nuclear proteins by poly(ADP ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be

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